EXPLORING ANTICANDIDAL AND ANTIBIOFILM POTENTIALS OF SYNTHESIZED N-(SUBSTITUTEDBENZYLIDENE)-4,6-DIMETHOXYPYRIMIDIN-2-AMINE ANALOGUES
نویسندگان
چکیده
منابع مشابه
N-Benzylpyridin-2-amine
In the crystal of the title compound, C(12)H(12)N(2), inter-molecular N-H⋯N hydrogen bonds form rings of graph-set motif R(2) (2)(8) and C-H⋯π inter-actions further consolidate the dimers. Neighbouring dimers are further connected into a three-dimensional network by C-H⋯π inter-actions. The benzyl and pyridyl rings form a dihedral angle of 67.2 (1)°
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The title new diquinaldine derivative, C27H24N4, forms molecular assemblies organized by intermolecular quinoline pi-pi stacking [3.356 (3) and 3.440 (3) A] and both inter- and intramolecular N-H...N hydrogen bonds [3.039 (3)-3.104 (3) A and 129 (2)-172 (2) degrees]. The combination of such interactions provides readily definable contacts that propagate along each crystallographic axis.
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The title compound, C(15)H(13)ClN(6), contains two pyrimidine rings and one benzene ring, where the dihedral angle between the planes through the pyrimidine rings is 81.57 (10)°, and those between the pyrimidine rings and the benzene ring are 84.02 (8) and 89.46 (7)°, indicating that the three rings are almost perpendicular. In the crystal, inter-molecular N-H⋯N hydrogen bonds link the mol-ecul...
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The title compound, C(11)H(11)N(3), crystallizes with two mol-ecules (A and B) in the asymmetric unit. The geometries of both mol-ecules are very similar, with the exception of the torsion angles of the inter-ring chains; the values for C-N-C-C are 67.4 (5) and -69.3 (5)° for mol-ecules A and B, respectively. The dihedral angles between the pyridyl ring planes are 84.0 (2) and 83.2 (2)° for mol...
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ژورنال
عنوان ژورنال: Bulletin of Pharmaceutical Sciences
سال: 2022
ISSN: ['1110-0052']
DOI: https://doi.org/10.21608/bfsa.2022.271592